Cicilia Windiyaningsih
University of Respati | Indonesia
Title: Treatment of Cotrimoxazole prevention significantly improved CD 4 in HIV/AIDS patients
Biography
Biography: Cicilia Windiyaningsih
Abstract
Background: WHO estimates at year 2014 there were 9.6 million peoples worldwide suffering from TB. One third of the 37
million peoples living with HIV worldwide were infected by latent TB, in which people with latent TB were at risk 26 times
(24-28) to become patients with active TB. In September 2014, the cumulative cases of HIV in Indonesia were 150,296 cases
with the number of people living with HIV who were receiving ARV treatment as many as 45,631 peoples, and TB was the most
opportunistic infection in people living with HIV in Hospital Infection Dr. Sulianti Saroso in year 2013 until year 2016, despite
the number of people living of HIVAIDS +TB was decreased ( year 2013 amount 29,50%, 2016 amount 22,02% (Adria Rusli.
2016). Purpose of research to determine the determinant influence of HIVAIDS +TBC.
Research Method: This research was a quantitative with case control study using secondary data in medical record. The
study population in this study was all patients of TB-HIV Co-Infection at Infectious Hospital Dr. Sulianti Saroso, Jakarta at
2013-2016. The sample in the study was calculated using lemeshow formula amount 160 for cases and 160 controls taken
by the ramdom sampling technique. Data analysis was done by univariate, bivariate and multivariate with multiple logistic
regression.
Result: The final model of multivariate analysis has showed the variables were influenced of HIV-AIDS+Tb control with
HIV-AIDS that were access to health facilities (p 0.001, OR 3,517, 95% CI 1.828-6.766) weight loss (P 0.001, OR 0.180,
95%CI 0.095—0.338), comorbid with other opportunistic infections (p 0,001; OR 4.617,95%CI 1.876-11.363); CD4 cell count 6
months after ARV (p 0,001; OR 15.769,95%CI 8.286-30.008). All patients have given treatment of Cotrimoxazole to prevention.
Conclusions: Difficult access, body weight decreased more than 7 kg, there were comorbidity, CD 4 <350 sel / mm3 have
influenced for HIVAIDS +TBC. That variables have contributed for HIVAIDS +TBC 52,3%.